Bruno Cammue is a visiting PI (10%) at PSB.
Research on Plant Fungi Interactions (PFIs) was initiated in the early 1990s with an extensive screening for novel antimicrobial plant peptides, and resulted in the discovery of several types of novel antifungal proteins. On one of them, named the plant defensins (PDFs), pioneering research was continued. PDFs are small, basic, cysteine-rich antifungal peptides that are structurally related to insect and mammalian defensins. They are active against a broad range of phytopathogenic fungi (e.g. Botrytis cinerea, Fusarium spp., Alternaria spp.) and even human pathogens (e.g. Candida albicans and Aspergillus flavus), whereas they are nontoxic to plant and mammalian cells. Primarily based on PDF studies, research on PFIs was further developed in the late 1990s in two closely collaborating research units, focused on each side of the plant-fungus interaction, being the Plant Unit and the Fungus/Yeast Unit, respectively.
For a full overview of his research projects including fungus and yeast research, please refer to: